Markets tumble ahead of Chinese trade talks

The markets tumbled to close lower with the Dow plunging 174 points to 23,924 as the U.S. trade delegation prepares to meet with Chinese officials. Nasdaq fell 29 points to 7100.

On the upside

InVivo Therapeutics (Nasdaq: NVIV) presented the complete six-month primary endpoint results from the INSPIRE study of the investigational Neuro-Spinal Scaffold in acute thoracic complete spinal cord injury.

Nanometrics (Nasdaq: NANO) impressed with sharply higher first quarter earnings and revenue that beat analyst expectations by a wide margin.

Frontier Communications (Nasdaq: FTR) narrowed first quarter losses more than expected.

On the downside

Esperion Therapeutics (Nasdaq: ESPR) reported a wider than expected loss for the first quarter and announced positive results from Phase 3 study of bempedoic acid but 13 patients died.

TC Pipelines (NYSE: TCP) lowered its quarterly cash distribution.

Capital Senior Living (NYSE: CSU) reported a loss for the first quarter as revenue slipped.

In the broad market, declining issues barely edged out advancers by a slim margin on the NYSE while advancers outpaced decliners by nearly 6 to 5 on Nasdaq. The broader S&P 500 dropped 19 points to 2,635. Bitcoin slipped $2 to $9,217.

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