Filed pursuant to Rule 433

Registration Statement 333-187080

Thermo Fisher Scientific Inc.

Term Sheet

November 30, 2015

2.150% Senior Notes due 2018


Issuer:    Thermo Fisher Scientific Inc.
Principal Amount:    $450,000,000
Maturity Date:    December 14, 2018
Coupon (Interest Rate):    2.150%
Yield to Maturity:    2.151%
Benchmark Treasury:    1.25% due November 15, 2018
Spread to Benchmark Treasury:    T + 92 bps
Benchmark Treasury Price and Yield:    100-1 34 / 1.231%
Interest Payment Dates:    December 15 and June 15, commencing on June 15, 2016
Redemption Provision:    At any time and from time to time, the issuer may redeem the notes, in whole or in part at its option, at a redemption price equal to the greater of (1) 100% of the principal amount of the notes to be redeemed and (2) the sum of the present values of the remaining scheduled payments of principal and interest in respect of the notes being redeemed (not including any portion of the payments of interest accrued but unpaid as of the date of redemption) discounted on a semi-annual basis (assuming a 360-day year of twelve 30-day months), at the Treasury Rate plus 15 basis points, plus accrued and unpaid interest, if any, to, but excluding, the date of redemption.
Issue Price:    99.997%
Settlement Date:    December 9, 2015 (T+7)
Current Ratings*:   

Moody’s: Baa3 (Positive)

S&P: BBB (Stable)

Fitch: BBB (Stable)

CUSIP:    883556 BL5
ISIN:    US883556BL50
Joint Book-Running Managers:   

Goldman, Sachs & Co.

J.P. Morgan Securities LLC

Mizuho Securities USA Inc.

* A securities rating is not a recommendation to buy, sell or hold securities and may be subject to revision or withdrawal at any time. Credit ratings are subject to change depending on financial and other factors.

The issuer has filed a registration statement (including a prospectus) with the SEC for the offering to which this communication relates. Before you invest, you should read the prospectus in that registration statement and other documents the issuer has filed with the SEC for more complete information about the issuer and this offering. You may get these documents for free by visiting EDGAR on the SEC Web site at www.sec.gov. Alternatively, the active joint book-running managers can arrange to send you the prospectus if you request it by calling Goldman, Sachs & Co. at 1-866-471-2526; or by calling J.P. Morgan Securities LLC at 1-212-834-4533; or by calling Mizuho Securities USA Inc. at 1-866-271-7403.